Evidence on mechanical prophylaxis
Systematic reviews and meta-analyses show that intermittent pneumatic compression significantly reduces the risk of venous thromboembolism in surgical patients compared with no prophylaxis.
The effectiveness depends on the setting and risk profile: in the high-risk range — for example in orthopaedic joint replacement — guidelines generally recommend a combined mechanical and pharmacological prophylaxis. Where medication is contraindicated, mechanical prophylaxis can be the primary measure.
Further reading
- S3 guideline on VTE prophylaxis (AWMF 003-001) — framing of mechanical prophylaxis
- Mode of action of IPC — mechanism and areas of use